|
KMID : 0882420150890060719
|
|
Korean Journal of Medicine
2015 Volume.89 No. 6 p.719 ~ p.722
|
|
|
Skeletal Muscle Metastasis and Elevated β-HCG Level Secondary to Tongue Cancer: a Case Report and Review of Literature
|
|
Ham Jun-Soo
Hwang Keum-Bit
Hwang Su-bin
Jeong Suk-Hyeon
Lee Jee-Yun
Lee Se-Hoon
Park Keun-Chil
|
|
|
Abstract
|
|
|
|
Metastases to skeletal muscle and paraneoplastic syndromes involving β-human chorionic gonadotropin (HCG) production are an extremely rare manifestation of head and neck squamous cell carcinoma. We report a patient with a β-HCG-secreting squamous cell carcinoma of the tongue with diffuse metastases involving skeletal muscle. A 47 year old female, who was being treated heavily with palliative chemotherapy for metastatic tongue cancer, was admitted with a palpable thigh mass and pain. A magnetic resonance image showed an intramuscular metastasis in the thigh. Ultrasound-guided biopsy of the thigh mass confirmed metastatic squamous cell carcinoma. She was scheduled for enrollment into a clinical trial; however, a positive serum β-HCG test was noticed. There was no evidence of pregnancy or a trophoblastic or non-trophoblastic tumor secreting β-HCG. Finally, she was revealed to have a paraneoplastic syndrome with diffuse metastases and was ultimately referred for palliative care. We review the literature of previously reported cases of an increase of β-HCG in patients with head and neck cancer.
|
|
|
KEYWORD
|
|
|
Tongue neoplasms, Head and neck neoplasms, Chorionic gonadotropin, beta Subunit, Human, Muscle, Skeletal
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|